Fructose Isn’t Just Sugar. It Acts More Like a Hormone

A new review says we’ve had fructose wrong for decades. The nine authors, led by Richard Johnson at the University of Colorado Anschutz, argue that fructose “is not just another calorie.” It is a signal. It tells the liver to make fat and brace for a famine that never comes. That made sense for a bear fattening up on autumn berries. It makes less sense for a person drinking soda in March.

The review reframes the WHO’s sugar guideline, argues ScienceBlog.com, as “less a recommendation about calories and more a warning about a signalling molecule we have been dosing ourselves with, several times a day, for most of a century.”