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Study Finds Tattoo Ink Moves Through the Body, Killing Immune Cells

Published by admin on December 3, 2025

Tattoo ink doesn’t just sit inertly in the skin. New research shows it moves rapidly into the lymphatic system, where it can persist for months, kill immune cells, and even disrupt how the body responds to vaccines. Scientists in Switzerland used a mouse model to trace what happens after tattooing. Pigments drained into nearby lymph nodes within minutes and continued to accumulate for two months, triggering immune-cell death and sustained inflammation. The ink also weakened the antibody response to Pfizer Inc. and BioNTech SE’s COVID vaccine when the shot was administered in tattooed skin. In contrast, the same inflammation appeared to boost responses to an inactivated flu vaccine. “This work represents the most extensive study to date regarding the effect of tattoo ink on the immune response and raises serious health concerns associated with the tattooing practice,” the researchers said. “Our work underscores the need for further research to inform public health policies and regulatory frameworks regarding the safety of tattoo inks.”

The findings have been published in the journal Proceedings of the National Academy of Sciences.

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