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Old Hearts Become Biologically Younger When Transplanted Into Younger People

Published by admin on October 6, 2026

It might be reasonable to think that there’s an indelible link between the heart and the body it resides in — the processes that affect one inevitably affect the other. But a new preprint, uploaded to bioRxiv and yet to be peer-reviewed, suggests that this may only be true up to a point. Take the heart out of the body and put it in a new one, and something incredible happens. The transplanted heart begins to take on the biological age of its new owner. Older hearts transplanted into younger recipients appear to become biologically younger, while younger hearts placed in older bodies show signs of accelerated aging.

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