Psychedelic Drugs May Launch a New Era in Psychiatric Treatment, Brain Scientists Say

One of the hottest tickets at this year’s Society for Neuroscience meeting in San Diego was a session on psychedelic drugs. About 1,000 brain scientists squeezed into an auditorium at the San Diego Convention Center for the symposium, called Psychedelics and Neural Plasticity. They’d come to hear talks on how drugs like psilocybin and MDMA can alter individual brain cells, can help rewire the brain, and may offer a new way to treat disorders ranging from depression to chronic pain.

[…] Brain plasticity may explain why a single dose of a psychedelic drug can have a long-lasting impact on disorders like anxiety, depression and PTSD. “It can be months or years,” says Dr. Gitte Knudsen a neurologist from University of Copenhagen in Denmark who spoke at the psychedelics session. “It’s a stunning effect.” These long-term effects have been shown with drugs including psilocybin, LSD and DMT (ayahuasca), Knudsen says. In contrast, most existing psychiatric drugs need to be taken every day. But psychedelic drugs have some drawbacks. They can cause nausea or produce hallucinations that are frightening or unpleasant.